Mon premier blog

Pathology and Genetics: Tumours of Haematopoietic and Lymphoid Tissues (World Health Organization Classification of Tumours) Elaine Sarkin Jaffe
Publisher:

The classification of adult SM patients per the 2008 World Health Organization (WHO) system1 has been validated for its prognostic utility.2 In addition to WHO SM subtype, an independent association between inferior survival and advanced age, weight loss, anemia, thrombocytopenia, hypoalbuminemia and . Leukemias are classified according to clinical, morphologic, and immunologic phenotypes, caused by specific genetic aberrations in association to distinct prognostic profiles. Lyon, France: IARC Press, 2001. Primary brain tumours in adults. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues is the second volume of the 4th Edition of the WHO series on histological and genetic typing of human tumours. Br J Dermatol 1992; 126: 596 - 602. In 1982 With the advancement of immunology and genetics, the characterization and algorithm of lymphomas have been taken over by the World Health Organization (WHO) Lymphoma Classification. Jaffe ES, Harris NL, Stein H, Vardiman JW. The recent and ongoing rapid WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue is the third volume in the new WHO series on histological and genetic typing of human tumors. There followed a series of reports, predominantly from Japan and East Asia, demonstrating the striking pathological feature of EBV-infected T or NK cells in the blood or tissue of affected patients [20-26]. Extra-nodal NK/T -cell lymphoma (ENKTL) is a relatively recently characterised clinicopathological entity, being formally incorporated into the WHO classification of haematopoietic and lymphoid tumours in 1999 [86]. In the late 1970s and early 1980s the term “reticulum cell sarcoma” became a misnomer as researchers demonstrated the origin of the tumor cells to be transformed lymphoid cells (malignant B- and T- lymphocytes), not histiocytes. In: Jaffe ES, Harris NL, Stein H, et al., eds.: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. Pathology and Genetics of Head and Neck Tumours is the latest volume in the new WHO series on histological and genetic typing of human tumours. (2001) in World Health Organization Classification of Tumours. New knowledge of disease molecular pathology, cytogenetic, epigenetic and genomic alterations have provided new strategies to attack and eradicate tumor cells at molecular level and significantly impacted our current therapeutics for hematological malignancies. World Health Organization Classification of Tumours, 3, pp 77-80. WHO World Health Organization classification of tumours. In: Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, et al (eds) WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues 4th edn. This authoritative, concise reference book provides an Summary.